Establishment of reference intervals of biochemical analytes for healthy Chinese volunteers during the screening process in clinical pharmacology trials

Establishment of reference intervals of biochemical analytes for healthy Chinese volunteers during the screening process in clinical pharmacology trials

Objectives: The laboratory reference intervals (gathering) plays a key role in clinical pharmacology trials, both in the screening process and in evaluating drug safety. However, the get-togethers tend to be confined to the general population, and data on residents get-togethers for a limited trial. The purpose of this study was to determine the appropriate get-togethers for use when screening specifically defined subgroups of healthy Chinese population in clinical pharmacology trials.


Methods: A total of 773 healthy Chinese volunteers (552 men and 221 women) who try to participate in clinical pharmacology trials were included in this study. Sixteen different biochemical analytes measured by Beckman Coulter Unicel DXC 800 automatic analyzer. Get-togethers, which are partitioned by gender using the Harris and Boyd and calculated using non-parametric methods.


Results: gatherings of 16 analytes biochemical for a healthy Chinese volunteers during the screening process in clinical pharmacology trials reported in this study. striking differences between get-togethers in this study and gathering provided by our laboratory or the existing literature was also observed. Compared with our institutional gatherings, get-togethers newly established more applicable to the population of the current session.


Conclusion: The get-together in this study can serve as a powerful clinical tool for the screening process in clinical pharmacology trials. However, these gatherings should be re-verified if any circumstances change. These results also emphasize the importance of rebuilding the gatherings are more applicable for testing local population.

 Establishment of reference intervals of biochemical analytes for healthy Chinese volunteers during the screening process in clinical pharmacology trials
Establishment of reference intervals of biochemical analytes for healthy Chinese volunteers during the screening process in clinical pharmacology trials

False, marked leukocytosis in 2 cats with Heinz body hemolytic anemia

Two domestic shorthair cat presented with anorexia and dehydration after intake of caramelized onions. Delivering the key findings from the CBC (ADVIA 2120), serum biochemistry, and urinalysis including counterfeit, marked leukocytosis with discordant basophils (BASO) channel and channel number WBC peroxidase, the directions normal leukocyte number, light, anemia non-regenerative the difference between automatic and the number of reticulocytes, the abundance of large Heinz body (HBs), and scattergrams very irregular.

Case 1 also shows the concentration was significantly increased average living cell hemoglobin (MCHC) and the difference between the index of RBC hemoglobin. Results leukocytes fake confirmed through re-analysis of samples (including the acquisition of new samples, use an analysis of alternatives (Sysmex XT-2000iV; Case 1 only), and evaluation of scattergrams and blood films (Cases 1 and 2).

Repeatedly the number of discrepant reticulocytes also identified . in both cases, the wrong number of BASO WBC, the difference in the number of reticulocytes and index of RBC, and scattergrams atypical interpreted with results from the various effects of HBs, these cases emphasize the importance of reviewing the film of blood, interpret scattergrams, and usefulness of the method duplicates to determine various measurands on a hematology analyzer.

Cefuroxime (sodium)

HY-B1256 1g
EUR 192

Cefuroxime

GA9610-100MG 100 mg
EUR 84

Cefuroxime

GA9610-1G 1 g
EUR 187.2

Cefuroxime

GA9610-250MG 250 mg
EUR 112.8

Thyroxine (Sodium salt)

30-AT52 1 gram
EUR 422.4
Description: High purity Thyroxine sodium salt

Triiodothyronine (Sodium salt)

30-AT53 1 gram
EUR 1018.8
Description: High purity (>99%) Triiodothyronine sodium salt

Ampicillin, Sodium Salt

A4004-005 5g
EUR 111.6

Ampicillin, Sodium Salt

A4004-025 25g
EUR 206.4

Ampicillin, Sodium Salt

A4004-100 100g
EUR 370.8

Sivelestat sodium salt

A4430-10 10 mg
EUR 205.2
Description: Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-?B activation and LTB4-induced neutrophil transmigration in vitro.

Sivelestat sodium salt

A4430-25 25 mg
EUR 408
Description: Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-?B activation and LTB4-induced neutrophil transmigration in vitro.

Sivelestat sodium salt

A4430-5 5 mg
EUR 141.6
Description: Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-?B activation and LTB4-induced neutrophil transmigration in vitro.

Sivelestat sodium salt

A4430-50 50 mg
EUR 673.2
Description: Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-?B activation and LTB4-induced neutrophil transmigration in vitro.

Fostriecin sodium salt

A4536-.1 100 µg
EUR 584.4
Description: IC50: Inhibit protein phosphatase types 2A (PP2A) and 4 (PP4) intensively with an IC50 of 1.5 nM and 3 nM respectively. Inhibit topoisomerase II (Topo II) and protein phosphatase type 1 (PP1) slightly with an IC50 of 40 ?M and 131 ?M respectively.

Fostriecin sodium salt

A4536-.5 500 µg
EUR 1762.8
Description: IC50: Inhibit protein phosphatase types 2A (PP2A) and 4 (PP4) intensively with an IC50 of 1.5 nM and 3 nM respectively. Inhibit topoisomerase II (Topo II) and protein phosphatase type 1 (PP1) slightly with an IC50 of 40 ?M and 131 ?M respectively.

Cefotaxime Sodium Salt

20-abx082178
  • EUR 260.40
  • EUR 210.00
  • 100 mg
  • 5 g

PIPES Sodium Salt

20-abx082438
  • EUR 326.40
  • EUR 226.80
  • 250 g
  • 25 g

Carboxymethylcellulose sodium salt

abx082467-100g 100 g
EUR 226.8

Ampicillin Sodium Salt

abx082587-5g 5 g
EUR 210

Cefotaxime Sodium Salt

abx188641-100g 100 g
EUR 610.8

Tianeptine Sodium Salt

abx188914-25g 25 g
EUR 376.8

Ampicillin Sodium Salt

AK0839-0010 10g Ask for price

Ampicillin Sodium Salt

AK0839-0025 25g Ask for price

Ampicillin Sodium Salt

AK0839-0100 100g Ask for price

Heparin Sodium Salt

AK3004-1000 1g Ask for price

Heparin Sodium Salt

AK3004-5000 5g Ask for price

Proglumide sodium salt

B5121-100 100 mg
EUR 166.8

Proglumide sodium salt

B5121-5.1 10 mM (in 1mL DMSO)
EUR 180

GSK1349572 sodiuM salt

B5856-10 10 mg
EUR 379.2
Description: Integrase inhibitors are a new class of antiretroviral drugs blocking the action of HIV integrase, which catalyses several key steps in the life cycle of the virus and is essential for insertion of the viral genome into the host cell DNA. GSK1349572 is a next-generation HIV integrase (IN) inhibitor.

GSK1349572 sodiuM salt

B5856-100 100 mg
EUR 1452
Description: Integrase inhibitors are a new class of antiretroviral drugs blocking the action of HIV integrase, which catalyses several key steps in the life cycle of the virus and is essential for insertion of the viral genome into the host cell DNA. GSK1349572 is a next-generation HIV integrase (IN) inhibitor.

GSK1349572 sodiuM salt

B5856-5 5 mg
EUR 289.2
Description: Integrase inhibitors are a new class of antiretroviral drugs blocking the action of HIV integrase, which catalyses several key steps in the life cycle of the virus and is essential for insertion of the viral genome into the host cell DNA. GSK1349572 is a next-generation HIV integrase (IN) inhibitor.

GSK1349572 sodiuM salt

B5856-50 50 mg
EUR 873.6
Description: Integrase inhibitors are a new class of antiretroviral drugs blocking the action of HIV integrase, which catalyses several key steps in the life cycle of the virus and is essential for insertion of the viral genome into the host cell DNA. GSK1349572 is a next-generation HIV integrase (IN) inhibitor.

Resazurin sodium salt

B6098-1000 1 g
EUR 100.8
Description: The non-fluorescent resazurin has been used as a fluorogenic oxidation-reduction indicator in various cells by flow cytometry, fluorescence microscopy and high-throughput screening. Its red-fluorescent product, resorufin, has absorption/emission maxima ~575/585 nm.

Resazurin sodium salt

B6098-5000 5 g
EUR 199.2
Description: The non-fluorescent resazurin has been used as a fluorogenic oxidation-reduction indicator in various cells by flow cytometry, fluorescence microscopy and high-throughput screening. Its red-fluorescent product, resorufin, has absorption/emission maxima ~575/585 nm.

Dantrolene, sodium salt

B6329-100 100 mg
EUR 158.4

Dantrolene, sodium salt

B6329-5.1 10 mM (in 1mL DMSO)
EUR 129.6

Entacapone sodium salt

B1090-10 10 mg
EUR 166.8
Description: Entacapone, a nitrocatechol compound, is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT), a Mg2+-dependent enzyme involved in the metabolism of catecholamines and catechol compounds.

Entacapone sodium salt

B1090-100 100 mg
EUR 385.2
Description: Entacapone, a nitrocatechol compound, is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT), a Mg2+-dependent enzyme involved in the metabolism of catecholamines and catechol compounds.

Entacapone sodium salt

B1090-50 50 mg
EUR 277.2
Description: Entacapone, a nitrocatechol compound, is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT), a Mg2+-dependent enzyme involved in the metabolism of catecholamines and catechol compounds.

Adapalene sodium salt

B1277-100 100 mg
EUR 170.4
Description: Adapalene sodium salt, a synthetic retinoid, is a Retinoic acid receptor agonist (RAR).

Adapalene sodium salt

B1277-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Adapalene sodium salt, a synthetic retinoid, is a Retinoic acid receptor agonist (RAR).

Adapalene sodium salt

B1277-50 50 mg
EUR 129.6
Description: Adapalene sodium salt, a synthetic retinoid, is a Retinoic acid receptor agonist (RAR).

HEPES Sodium salt

B7303-250000 250 g
EUR 343.2

CHPG Sodium salt

B7475-10 10 mg
EUR 303.6

CHPG Sodium salt

B7475-50 50 mg
EUR 1082.4

Nigericin sodium salt

B7644-10 10 mg
EUR 157.2
Description: Nigericin sodium salt is an ionophore that exchanges K+ for H+ across biological membranes.Ionophore is a lipid-soluble molecule that transports ions across the cell membrane.

Nigericin sodium salt

B7644-25 25 mg
EUR 254.4
Description: Nigericin sodium salt is an ionophore that exchanges K+ for H+ across biological membranes.Ionophore is a lipid-soluble molecule that transports ions across the cell membrane.

Nigericin sodium salt

B7644-5 5 mg
EUR 122.4
Description: Nigericin sodium salt is an ionophore that exchanges K+ for H+ across biological membranes.Ionophore is a lipid-soluble molecule that transports ions across the cell membrane.

Bialaphos (sodium salt)

B7852-100 100 mg
EUR 289.2
Description: The antibiotic bialaphos (or SF1293) is a natural non-selective phytotoxin produced by Streptomyces hygroscopicus. Bialaphos is a tripeptide consisting of two L-alanine molecules and an L-glutamic acid analogue called phosphinothricin.

Bialaphos (sodium salt)

B7852-50 50 mg
EUR 216
Description: The antibiotic bialaphos (or SF1293) is a natural non-selective phytotoxin produced by Streptomyces hygroscopicus. Bialaphos is a tripeptide consisting of two L-alanine molecules and an L-glutamic acid analogue called phosphinothricin.

Sulfamerazine sodium salt

B3430-100000 100 g
EUR 164.4
Description: Sulfamerazine Sodium is a sulfonamide antibacterial.

Sulfamerazine sodium salt

B3430-50000 50 g
EUR 132
Description: Sulfamerazine Sodium is a sulfonamide antibacterial.

GSK2190915 sodium salt

B4905-10 10 mg
EUR 514.8

GSK2190915 sodium salt

B4905-5 5 mg
EUR 332.4

GSK2190915 sodium salt

B4905-5.1 10 mM (in 1mL DMSO)
EUR 456

GSK2190915 sodium salt

B4905-50 50 mg
EUR 1858.8

Ischemin sodium salt

B4917-10 10 mg
EUR 321.6

Ischemin sodium salt

B4917-50 50 mg
EUR 1167.6

Azlocillin sodium salt

B1893-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Azlocillin is an acylampicillin with a broad spectrum against bacteria.

Azlocillin sodium salt

B1893-50 50 mg
EUR 153.6
Description: Azlocillin is an acylampicillin with a broad spectrum against bacteria.

Azlocillin sodium salt

B1893-S Evaluation Sample
EUR 97.2
Description: Azlocillin is an acylampicillin with a broad spectrum against bacteria.

(±)-Cloprostenol sodium salt

B7004-1 1 mg
EUR 134.4

(±)-Cloprostenol sodium salt

B7004-10 10 mg
EUR 435.6

(±)-Cloprostenol sodium salt

B7004-5 5 mg
EUR 360

CAPS, sodium salt

CB0097 50g
EUR 86.1

CAPSO, sodium salt

CD0041 50g
EUR 91.32

Hepes, Sodium Salt

CH039 25 g
EUR 141.6

Hepes, Sodium Salt

CH040 100 g
EUR 202.8

Hepes, Sodium Salt

CH041 500 g
EUR 448.8

Cefamandole sodium salt

C079-100MG 100 mg
EUR 177.6

Cefamandole sodium salt

C079-500MG 500 mg
EUR 568.8

Methicillin (sodium salt)

C3238-100 100 mg
EUR 174
Description: Methicillin is a semisynthetic penicillin antibiotic.In vitro: Similar to other ?-lactam antibiotics, meticillin acts via inhibiting the synthesis of bacterial cell walls.

Methicillin (sodium salt)

C3238-250 250 mg
EUR 271.2
Description: Methicillin is a semisynthetic penicillin antibiotic.In vitro: Similar to other ?-lactam antibiotics, meticillin acts via inhibiting the synthesis of bacterial cell walls.

Methicillin (sodium salt)

C3238-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Methicillin is a semisynthetic penicillin antibiotic.In vitro: Similar to other ?-lactam antibiotics, meticillin acts via inhibiting the synthesis of bacterial cell walls.

Methicillin (sodium salt)

C3238-50 50 mg
EUR 129.6
Description: Methicillin is a semisynthetic penicillin antibiotic.In vitro: Similar to other ?-lactam antibiotics, meticillin acts via inhibiting the synthesis of bacterial cell walls.

Ertapenem (sodium salt)

C3451-10 10 mg
EUR 289.2
Description: Ertapenem, the first group of carbapenems, is a 1-?-methyl carbapenem with potent in vitro activity against a broad spectrum of bacterial pathogens including Gram-positive and Gram-negative aerobic and anaerobic pathogens [1].

Ertapenem (sodium salt)

C3451-25 25 mg
EUR 537.6
Description: Ertapenem, the first group of carbapenems, is a 1-?-methyl carbapenem with potent in vitro activity against a broad spectrum of bacterial pathogens including Gram-positive and Gram-negative aerobic and anaerobic pathogens [1].

Ertapenem (sodium salt)

C3451-5 5 mg
EUR 195.6
Description: Ertapenem, the first group of carbapenems, is a 1-?-methyl carbapenem with potent in vitro activity against a broad spectrum of bacterial pathogens including Gram-positive and Gram-negative aerobic and anaerobic pathogens [1].

Cefamandole (sodium salt)

C3541-100 100 mg
EUR 292.8
Description: MIC: 0.25-2 mg/L for different E. coli strainsCefamandole is a cephalosporin antibiotic.The cephalosporins are a class of ?-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as "Cephalosporium".

Cefamandole (sodium salt)

C3541-50 50 mg
EUR 182.4
Description: MIC: 0.25-2 mg/L for different E. coli strainsCefamandole is a cephalosporin antibiotic.The cephalosporins are a class of ?-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as "Cephalosporium".

Cefamandole (sodium salt)

C3541-500 500 mg
EUR 710.4
Description: MIC: 0.25-2 mg/L for different E. coli strainsCefamandole is a cephalosporin antibiotic.The cephalosporins are a class of ?-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as "Cephalosporium".

Lorglumide (sodium salt)

C4809-25 25 mg
EUR 174
Description: Lorglumide (sodium salt) is the first nonpeptidic, selective and potent inhibitor of the CCK-A receptor [1][2][3][4] .

Lorglumide (sodium salt)

C4809-50 50 mg
EUR 205.2
Description: Lorglumide (sodium salt) is the first nonpeptidic, selective and potent inhibitor of the CCK-A receptor [1][2][3][4] .

Cefoxitin (sodium salt)

C4849-1000 1 g
EUR 289.2
Description: Cefoxitin (sodium salt) is a second generation cephalosporin antibiotic that was used to treat a wide range of gram-negative and gram-positive bacteria [1][2].

Cefoxitin (sodium salt)

C4849-250 250 mg
EUR 135.6
Description: Cefoxitin (sodium salt) is a second generation cephalosporin antibiotic that was used to treat a wide range of gram-negative and gram-positive bacteria [1][2].

Cefoxitin (sodium salt)

C4849-500 500 mg
EUR 196.8
Description: Cefoxitin (sodium salt) is a second generation cephalosporin antibiotic that was used to treat a wide range of gram-negative and gram-positive bacteria [1][2].

Fosmidomycin (sodium salt)

C4898-10 10 mg
EUR 498
Description: Fosmidomycin is a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXP) [1]. Fosmidomycin is an antibiotic originally isolated from bacteria of the genus Streptomyces.

Fosmidomycin (sodium salt)

C4898-25 25 mg
EUR 996
Description: Fosmidomycin is a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXP) [1]. Fosmidomycin is an antibiotic originally isolated from bacteria of the genus Streptomyces.

Fosmidomycin (sodium salt)

C4898-5 5 mg
EUR 292.8
Description: Fosmidomycin is a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXP) [1]. Fosmidomycin is an antibiotic originally isolated from bacteria of the genus Streptomyces.

Simvastatin (sodium salt)

C4426-100 100 mg
EUR 470.4
Description: Ki: 0.12 nMSimvastatin is a HMG-CoA reductase inhibitor. HMG-CoA reductase has been found to be the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the ?statin? class of cholesterol-lowering drugs.

Simvastatin (sodium salt)

C4426-25 25 mg
EUR 235.2
Description: Ki: 0.12 nMSimvastatin is a HMG-CoA reductase inhibitor. HMG-CoA reductase has been found to be the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the ?statin? class of cholesterol-lowering drugs.

Moniliformin (sodium salt)

C4459-1 1 mg
EUR 385.2
Description: Moniliformin induces mitotic arrest at the metaphase stage.Mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

Cefotaxime (sodium salt)

C4588-1000 1 g
EUR 151.2
Description: MIC: <0.1 ?g/ml for S. pneumoniae Cefotaxime is a cephalosporin antibiotic.

Cefotaxime (sodium salt)

C4588-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: MIC: <0.1 ?g/ml for S. pneumoniae Cefotaxime is a cephalosporin antibiotic.

Cefotaxime (sodium salt)

C4588-500 500 mg
EUR 129.6
Description: MIC: <0.1 ?g/ml for S. pneumoniae Cefotaxime is a cephalosporin antibiotic.

Cefotaxime (sodium salt)

C4588-5000 5 g
EUR 181.2
Description: MIC: <0.1 ?g/ml for S. pneumoniae Cefotaxime is a cephalosporin antibiotic.

Narasin (sodium salt)

C3061-25 25 mg
EUR 804
Description: IC50: 3.2 ?M: blocks NF-?B signaling via inhibition of I?B? phosphorylationNarasin, isolated from certain Streptomyces sp. is an ionophore antibiotic.

Narasin (sodium salt)

C3061-5 5 mg
EUR 224.4
Description: IC50: 3.2 ?M: blocks NF-?B signaling via inhibition of I?B? phosphorylationNarasin, isolated from certain Streptomyces sp. is an ionophore antibiotic.

Moxalactam (sodium salt)

C4121-1000 1 g
EUR 270
Description: Moxalactam (sodium salt) is a ?-lactam antibiotic.?-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most ?-lactam antibiotics act by inhibiting cell wall biosynthesis.

Moxalactam (sodium salt)

C4121-250 250 mg
EUR 134.4
Description: Moxalactam (sodium salt) is a ?-lactam antibiotic.?-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most ?-lactam antibiotics act by inhibiting cell wall biosynthesis.

Moxalactam (sodium salt)

C4121-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Moxalactam (sodium salt) is a ?-lactam antibiotic.?-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most ?-lactam antibiotics act by inhibiting cell wall biosynthesis.

Moxalactam (sodium salt)

C4121-500 500 mg
EUR 201.6
Description: Moxalactam (sodium salt) is a ?-lactam antibiotic.?-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most ?-lactam antibiotics act by inhibiting cell wall biosynthesis.

Cefazolin (sodium salt)

C4183-1000 1 g
EUR 201.6
Description: Cefazolin is a semisynthetic antibiotic with a broad spectrum of antibacterial activity. Cefazolin has exhibited high activity against Gram-positive bacteria and Gram-negative bacteria [1].

Cefazolin (sodium salt)

C4183-250 250 mg
EUR 126
Description: Cefazolin is a semisynthetic antibiotic with a broad spectrum of antibacterial activity. Cefazolin has exhibited high activity against Gram-positive bacteria and Gram-negative bacteria [1].

Cefazolin (sodium salt)

C4183-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Cefazolin is a semisynthetic antibiotic with a broad spectrum of antibacterial activity. Cefazolin has exhibited high activity against Gram-positive bacteria and Gram-negative bacteria [1].

Cefazolin (sodium salt)

C4183-500 500 mg
EUR 165.6
Description: Cefazolin is a semisynthetic antibiotic with a broad spectrum of antibacterial activity. Cefazolin has exhibited high activity against Gram-positive bacteria and Gram-negative bacteria [1].

Tazobactam (sodium salt)

C4245-1000 1 g
EUR 271.2
Description: Tazobactam is a ?-lactamase inhibitor [1]. Tazobactam shows intrinsic activity against Acinetobacter strains. The ?-Lactamases are responsible for resistance to penicillins, extended-spectrum cephalosporins, monobactams, and carbapenems.

Tazobactam (sodium salt)

C4245-250 250 mg
EUR 139.2
Description: Tazobactam is a ?-lactamase inhibitor [1]. Tazobactam shows intrinsic activity against Acinetobacter strains. The ?-Lactamases are responsible for resistance to penicillins, extended-spectrum cephalosporins, monobactams, and carbapenems.

Tazobactam (sodium salt)

C4245-500 500 mg
EUR 201.6
Description: Tazobactam is a ?-lactamase inhibitor [1]. Tazobactam shows intrinsic activity against Acinetobacter strains. The ?-Lactamases are responsible for resistance to penicillins, extended-spectrum cephalosporins, monobactams, and carbapenems.

Cefonicid (sodium salt)

C3812-1000 1 g
EUR 487.2
Description: Cefonicid is a second-generation cephalosporin antibiotic.Cephalosporins, the largest and most diverse family of antibiotics of the beta-lactam group, are structurally and pharmacologically related to the penicillins.

Cefonicid (sodium salt)

C3812-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Cefonicid is a second-generation cephalosporin antibiotic.Cephalosporins, the largest and most diverse family of antibiotics of the beta-lactam group, are structurally and pharmacologically related to the penicillins.

Cefonicid (sodium salt)

C3812-500 500 mg
EUR 301.2
Description: Cefonicid is a second-generation cephalosporin antibiotic.Cephalosporins, the largest and most diverse family of antibiotics of the beta-lactam group, are structurally and pharmacologically related to the penicillins.

Cefoperazone (sodium salt)

C3913-10000 10 g
EUR 483.6
Description: Cefoperazone is a new semisynthetic cephalosporin with a broad spectrum of antibacterial activity. Cefoperazone shows high activity against gram-positive bacteria and gram-negative bacilli, such as Escherichia coli, Klebsiella pneumoniae, and Proteus species [1].

Cefoperazone (sodium salt)

C3913-5000 5 g
EUR 320.4
Description: Cefoperazone is a new semisynthetic cephalosporin with a broad spectrum of antibacterial activity. Cefoperazone shows high activity against gram-positive bacteria and gram-negative bacilli, such as Escherichia coli, Klebsiella pneumoniae, and Proteus species [1].

Cefsulodin (sodium salt)

C5593-1000 1 g
EUR 268.8
Description: Cefsulodin, formerly named as SCE-129, is a cephalosporin with a spectrum of antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and most other gram-positive cocci [1].

Cefsulodin (sodium salt)

C5593-250 250 mg
EUR 147.6
Description: Cefsulodin, formerly named as SCE-129, is a cephalosporin with a spectrum of antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and most other gram-positive cocci [1].

Cefsulodin (sodium salt)

C5593-500 500 mg
EUR 216
Description: Cefsulodin, formerly named as SCE-129, is a cephalosporin with a spectrum of antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and most other gram-positive cocci [1].

Furegrelate (sodium salt)

C5692-10 10 mg
EUR 204
Description: Furegrelate (sodium salt) is a potent inhibitor of thromboxane synthase [1][2].Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) is a cytochrome P450 enzyme that catalyzes the conversion of prostaglandin H2 to thromboxane A2.

Furegrelate (sodium salt)

C5692-5 5 mg
EUR 134.4
Description: Furegrelate (sodium salt) is a potent inhibitor of thromboxane synthase [1][2].Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) is a cytochrome P450 enzyme that catalyzes the conversion of prostaglandin H2 to thromboxane A2.

Furegrelate (sodium salt)

C5692-50 50 mg
EUR 661.2
Description: Furegrelate (sodium salt) is a potent inhibitor of thromboxane synthase [1][2].Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) is a cytochrome P450 enzyme that catalyzes the conversion of prostaglandin H2 to thromboxane A2.

MES, sodium salt

MB0611 50g
EUR 89.23

MOPSO, sodium salt

MDB0095 25g
EUR 76.7

MOPS, sodium salt

MDB360S 100g
EUR 106.98

Methotrexate sodium salt

M031-250MG 250 mg
EUR 140.4

Monensin Sodium Salt

M083-1G 1 g
EUR 85.2

Monensin Sodium Salt

M083-5x1G 5 x 1 g
EUR 190.8

Pravastatin sodium salt

GK3699-50MG 50 mg
EUR 132

Saccharin sodium salt

GK7761-100G 100 g
EUR 54

Saccharin sodium salt

GK7761-1KG 1 kg
EUR 132

Saccharin sodium salt

GK7761-250G 250 g
EUR 69.6

Saccharin sodium salt

GK7761-500G 500 g
EUR 93.6

Xanthine sodium salt

GK7942-1G 1 g
EUR 112.8

Xanthine sodium salt

GK7942-250MG 250 mg
EUR 70.8

MCC950 sodium salt

GL1674-10MG 10 mg
EUR 661.2

MCC950 sodium salt

GL1674-1MG 1 mg
EUR 171.6

MCC950 sodium salt

GL1674-5MG 5 mg
EUR 440.4

Suramin sodium salt

GP0138-250MG 250 mg
EUR 370.8

Suramin sodium salt

GP0138-50MG 50 mg
EUR 132

Dantrolene sodium salt

GP0222-1G 1 g
EUR 112.8

Dantrolene sodium salt

GP0222-5G 5 g
EUR 217.2

Amoxicillin sodium salt

GP0775-1G 1 g
EUR 60

Amoxicillin sodium salt

GP0775-5G 5 g
EUR 122.4

Naproxen sodium salt

GP1072-25G 25 g
EUR 156

Naproxen sodium salt

GP1072-5G 5 g
EUR 93.6

Sulbactam sodium salt

GP3240-1G 1 g
EUR 84

Sulbactam sodium salt

GP3240-5G 5 g
EUR 151.2

Risedronate sodium salt

GP4398-1G 1 g
EUR 170.4

Risedronate sodium salt

GP4398-250MG 250 mg
EUR 98.4

Risedronate sodium salt

GP4398-50MG 50 mg
EUR 74.4

Citicoline sodium salt

GP4568-10G 10 g
EUR 103.2

Citicoline sodium salt

GP4568-25G 25 g
EUR 170.4

Citicoline sodium salt

GP4568-5G 5 g
EUR 76.8

Resazurin sodium salt

GP5198-1G 1 g
EUR 64.8

Resazurin sodium salt

GP5198-5G 5 g
EUR 112.8

Cefapirin sodium salt

GP5306-1G 1 g
EUR 189.6

Cefapirin sodium salt

GP5306-250MG 250 mg
EUR 103.2

Entacapone (sodium salt)

HY-14280A 10mg
EUR 142.8

Grazoprevir sodium salt

HY-15298C 10mg
EUR 291.6

Luminol (sodium salt)

HY-15922A 500mg
EUR 129.6

Salinomycin (sodium salt)

HY-17439 100mg
EUR 224.4

Heparin (sodium salt)

HY-17567A 500mg
EUR 176.4

Seladelpar sodium salt

HY-19522A 10mM/1mL
EUR 195.6

HEPES, sodium salt

HB0265 50g
EUR 78.79

HEPPSO, sodium salt

HB0496 25g
EUR 117.42

Etomoxir (sodium salt)

HY-50202A 5mg
EUR 176.4

Silmitasertib (sodium salt)

HY-50855B 10mg
EUR 224.4

Cefotaxime (sodium salt)

HY-A0088 10mM/1mL
EUR 135.6

Adapalene (sodium salt)

HY-B0091A 500mg
EUR 391.2

Cefoperazone (sodium salt)

HY-B0210A 500mg
EUR 129.6

Sulfamerazine (sodium salt)

HY-B0512A 500mg
EUR 157.2

Azlocillin (sodium salt)

HY-B0529A 500mg
EUR 135.6

Setogepram (sodium salt)

HY-100775 10mM/1mL
EUR 392.4

GJ103 (sodium salt)

HY-101203A 10mM/1mL
EUR 170.4

Moniliformin (sodium salt)

HY-101905 1mg
EUR 374.4

Nigericin (sodium salt)

HY-100381 100mg
EUR 870

Ceftizoxime sodium salt

GA1247-1G 1 g
EUR 98.4

Ceftizoxime sodium salt

GA1247-250MG 250 mg
EUR 70.8

Sulfamethazine sodium salt

GA1560-100G 100 g
EUR 103.2

Flucloxacillin sodium salt

GA1968-100MG 100 mg
EUR 274.8

Flucloxacillin sodium salt

GA1968-25MG 25 mg
EUR 132

Flucloxacillin sodium salt

GA1968-5MG 5 mg
EUR 74.4

Sulfathiazole sodium salt

GA2698-100G 100 g
EUR 151.2

Sulfathiazole sodium salt

GA2698-25G 25 g
EUR 74.4

Sulfamethoxazole sodium salt

GA2831-25G 25 g
EUR 112.8

Sulfamethoxazole sodium salt

GA2831-5G 5 g
EUR 69.6

Cefotaxime sodium salt

GA3583-1G 1 g
EUR 132

Cefotaxime sodium salt

GA3583-25G 25 g
EUR 600

Cefotaxime sodium salt

GA3583-5G 5 g
EUR 217.2

Piperacillin sodium salt

GA4134-1G 1 g
EUR 84

Piperacillin sodium salt

GA4134-5G 5 g
EUR 189.6


Data from 1164 patients admitted to our Department of Urology from January 2011 to July 2013 were retrospectively reviewed; 714 patients (age, 5-87 years; male: female ratio, 1.8: 1) exhibited urolithiasis, and 450 patients (age, 12-94 years; male: female ratio, 3.8: 1). Blood and urine are collected from patients morning after hospital admission. Serum and urine parameters examined by automatic biochemical analyzer. Statistical analyzes including Mann-Whitney U test and binary logistic regression.

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